Black cohosh is racemose.

From this plant, only the underground stem can be consumed in powder form or as an extract in tablet or liquid form. It must be standardized to contain certain triterpenes. Black cohosh does not contain phytoestrogens, which may explain its claimed estrogen-like effects, but it does contain small amounts of anti-inflammatory compounds, including salicylic acid.

Statements.

Black cohosh is said to be beneficial for menopausal symptoms (eg, hot flashes, mood lability, tachycardia, vaginal dryness), menstrual symptoms, and arthralgias in the case of rheumatoid arthritis or osteoarthritis.

Scientific evidence.

There is conflicting evidence regarding the benefits of treating menopausal symptoms (1). There is some reliable evidence of its effectiveness in other disorders and symptoms.

A recent review included 16 randomized controlled trials of women (n = 2027) taking oral black cohosh (median dose 40 mg). There was no difference in the incidence of hot flashes (3 studies; 393 women) or the assessment of climacteric symptoms (4 studies; 357 women) between black cohosh and placebo (1). A 2016 review of herbal products, including black cohosh, also found no benefit for treating menopausal symptoms. (2).

The lack of standardization of the dietary supplement used in research suggests that more research is needed to make a final decision. phyto

Side effects are rare. Headache and gastrointestinal upset are most likely. Dizziness, sweating, and hypotension may occur (with large doses).

In theory, black cohosh is contraindicated in patients with aspirin sensitivity, liver disease, hormone-sensitive cancers (such as certain types of breast cancer), stroke, or high blood pressure. The United States Pharmacopoeia (USP) has recommended, based on several case reports (3), that black cohosh products should be labeled with a warning that they may be hepatotoxic.

Drug interactions.

There is little clinical evidence that black cohosh affects drug action. However, a recent in vitro study suggests that black cohosh may inhibit the biotransformation or efficacy of tamoxifen and irinotecan, which are chemotherapeutic drugs (4).

Black cohosh reference material.

Leach MJ, Moore V: Black cohosh (Cimicifuga spp.) For menopausal symptoms. Cochrane Database Syst Rev 9: CD007244, 2012. doi: 10.1002 / 14651858.CD007244.pub2.

Franco OH, Chowdhury R, ​​et al: Use of plant-based therapies and menopausal symptoms: a systematic review and meta-analysis. JAMA 315 (23): 2554-63, 2016.doi: 10.1001 / jama.2016.8012.

Leave a Reply

Your email address will not be published.